모야모야병(Moyamoya disease)과 같은 대뇌 혈류장애를 보이는 환자에게 간접적으로 혈관재형성(Revascularization) 및 신생 혈관 생성(angiogenesis)을
유도하는 기술로, 다른 기술 대비 최소 침습적이며 약물 병합을 통해 보다 건강한 혈관을 생성시킬 수 있습니다.
논문
Hong et al., 2022, Stroke, Transdural Revascularization by Multiple Burrhole After Erythropoietin in Stroke Patients With Cerebral Hypoperfusion: A Randomized Controlled Trial.
Park et al., 2020, Neurobiology of diasease, Cranial burr hole with erythropoietin administration induces reverse arteriogenesis from the enriched extracranium
Hong et al., 2018, Stroke, Feasibility of multiple Burr hole with erythropoietin in acute Moyamoya patients.
임상
ClinicalTrials.gov Identifier: NCT02603406
Neovascularization Induced by Mechanical Barrier disrUption and Systemic Erythropoietin in Patients With Cerebral Perfusion Deficits (NIMBUS)